QuickView for LAMA5;jsessionid=D2F1781B3D6C029287C5E850EA91F435 (gene)

Gene Symbol:

LAMA5 Homo sapiens

Full name:

laminin subunit alpha 5

Synonyms:

laminin subunit alpha-5, laminin alpha-5 chain, laminin-10 subunit alpha, laminin-11 subunit alpha, laminin-15 subunit alpha

Genomic Location:

Chr 20: 60317516-60375763

Description:

This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. ...

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This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  TGGNNNNNNKCCAR_UNKNOWN ,  GCANCTGNY_MYOD_Q6 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  ARGGGTTAA_UNKNOWN ,  CAGCTG_AP4_Q5 ,  PPARA_02

Cytogenetic Map:

20q13.33

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