QuickView for LARS2 (gene)
- Gene Symbol:
- LARS2
Homo sapiens - Full name:
- leucyl-tRNA synthetase 2, mitochondrial
- Synonyms:
- HLASA, LEURS, PRLTS4, mtLeuRS, probable leucine--tRNA ligase, mitochondrial, leucine tRNA ligase 2, mitochondrial, leucine tRNA ligase 2, mitocondrial, leucine translase, probable leucyl-tRNA synthetase, mitochondrial
- Genomic Location:
- Chr 3: 45405079-45565332
- Description:
-
This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Schizosaccharomyces pombe , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
3p21.31
GO Molecular Function
ribonucleotide binding | carboxylic ester hydrolase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | aminoacyl-tRNA ligase activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | leucine-tRNA ligase activity | aminoacyl-tRNA editing activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | ligase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
RNA metabolic process | tRNA aminoacylation | cellular process | aminoacyl-tRNA metabolism involved in translational fidelity | cellular amino acid metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | peptide biosynthetic process | mitochondrial translation | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | small molecule metabolic process | cellular amide metabolic process | tRNA aminoacylation for protein translation | translation | biosynthetic process | aminoacyl-tRNA editing activity | peptide metabolic process | carboxylic acid metabolic process | tRNA metabolic process | protein metabolic process | metabolic process | mitochondrial gene expression | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | amide biosynthetic process | leucyl-tRNA aminoacylation | organic acid metabolic process | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of translational fidelity | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | membrane-enclosed lumen | intracellular
