QuickView for LCA (gene)

Gene Symbol:

Clta Mus musculus

Full name:

clathrin, light polypeptide (Lca)

Synonyms:

AV026556, Lca, clathrin light chain A, clathryn light chain (LCA2)

Genomic Location:

Chr 4: 44025515-44045718

Description:

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function a...

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Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACTTT_UNKNOWN ,  GATA1_01 ,  NFY_Q6 ,  NFY_01 ,  ETS2_B ,  E2F_Q3 ,  ALPHACP1_01 ,  E2F1DP1RB_01 ,  VDR_Q6 ,  ATGTTTC_MIR494 ,  ACACTAC_MIR1423P ,  GATTGGY_NFY_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-142-3p ,  Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-494

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