QuickView for LHB;jsessionid=A6B2424EA991201E8C635AEEE8F81E86 (gene)

Gene Symbol:

LHB Homo sapiens

Full name:

luteinizing hormone beta polypeptide

Synonyms:

CGB4, HH23, LSH-B, LSH-beta, lutropin subunit beta, interstitial cell stimulating hormone, beta chain, luteinizing hormone beta subunit, lutropin beta chain

Genomic Location:

Chr 19: 54211049-54212159

Description:

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation b...

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This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TATAAA_TATA_01 ,  EGR_Q6 ,  SMAD4_Q6

Cytogenetic Map:

19q13.33

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