QuickView for LOXL4 (gene)
- Gene Symbol:
- LOXL4
Homo sapiens - Full name:
- lysyl oxidase like 4
- Synonyms:
- LOXC, lysyl oxidase homolog 4, lysyl oxidase related C, lysyl oxidase-like 4 pseudogene, lysyl oxidase-like protein 4, lysyl oxidase-related protein C
- Genomic Location:
- Chr 10: 99997433-100017997
- Description:
-
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
10q24.2
GO Molecular Function
cation binding | protein-lysine 6-oxidase activity | catalytic activity | ion binding | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | copper ion binding | protein binding | scavenger receptor activity | oxidoreductase activity, acting on the CH-NH2 group of donors | transition metal ion binding | metal ion binding | cargo receptor activity | oxidoreductase activity
GO Biological Process
extracellular structure organization | peptidyl-amino acid modification | protein oxidation | establishment of localization | cellular process | localization | cellular component organization | protein-lysine 6-oxidase activity | supramolecular fiber organization | extracellular matrix organization | protein modification process | macromolecule modification | nitrogen compound metabolic process | vesicle-mediated transport | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | scavenger receptor activity | protein metabolic process | import into cell | metabolic process | oxidation-reduction process | peptidyl-lysine modification | endocytosis | organic substance metabolic process | oxidoreductase activity, acting on the CH-NH2 group of donors | collagen fibril organization | cellular protein metabolic process | receptor-mediated endocytosis | cellular protein modification process | peptidyl-lysine oxidation | cargo receptor activity | cellular metabolic process | oxidoreductase activity | macromolecule metabolic process
GO Cellular Component
receptor complex | protein-containing complex | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | membrane
