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QuickView for Lsm2 (gene)


Gene Symbol:
LSM2 Homo sapiens Homo sapiens
Full name:
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
Synonyms:
C6orf28, G7B, YBL026W, snRNP, U6 snRNA-associated Sm-like protein LSm2, LSM2 U6 small nuclear RNA and mRNA degradation associated, LSM2 homolog, U6 small nuclear RNA associated, protein G7b, small nuclear ribonuclear protein D homolog, snRNP core Sm-like protein Sm-x5
Genomic Location:
Chr 6: 31873152-31882722
Description:
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 6
6p21.33


Transcripts Names
NM_021177
Protein Names
Q6FGG1
Q9Y333



GO Molecular Function

GTPase binding | enzyme binding | nucleic acid binding | Ral GTPase binding | Ras GTPase binding | organic cyclic compound binding | protein binding | snRNA binding | small GTPase binding | U6 snRNA binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | RNA processing | nuclear-transcribed mRNA catabolic process, exonucleolytic | cellular process | organic substance catabolic process | regulation of metabolic process | catabolic process | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | RNA splicing | RNA splicing, via transesterification reactions | cellular nitrogen compound metabolic process | negative regulation of metabolic process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | regulation of gene expression | RNA catabolic process | aromatic compound catabolic process | cellular macromolecule catabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | gene expression | heterocycle metabolic process | cellular metabolic process | mRNA processing | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | mRNA splicing, via spliceosome | macromolecule metabolic process

GO Cellular Component

U6 snRNP | intracellular membrane-bounded organelle | catalytic complex | catalytic step 2 spliceosome | small nuclear ribonucleoprotein complex | U4/U6 x U5 tri-snRNP complex | cell | nuclear lumen | spliceosomal snRNP complex | ribonucleoprotein granule | cytoplasm | intracellular organelle | P-body | protein-containing complex | nucleoplasm | ribonucleoprotein complex | Lsm1-7-Pat1 complex | spliceosomal complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | membrane-enclosed lumen | cytosol | intracellular