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QuickView for Lysosome membrane protein II (biogroup)
- Description:
- Lysosome membrane protein II (LIMP II) is a 478-residue glycoprotein expressed in the membrane of lysosomes and secretory granules with lysosomal properties. The N-terminal segment (residues ~4-26) constitutes an uncleavable signal peptide. LIMP II possesses an additional C-terminal hydrophobic region that, together with the signal peptide, may anchor the protein to the membrane. The major portion of the protein resides on the luminal side and contains 11 potential N-glycosylation sites and 5 cysteine residues. The N- and C-terminal ends of the protein constitute short cytoplasmic tails. LIMP II is a subgroup of a larger family of the cell surface protein CD36 involved in cell adhesion.
- Taxonomy/Path:
- InterPro : CD36 family / Lysosome membrane protein II
SELECTED ORGANISM:
