Correlation Engine 2.0
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QuickView for MACROD2 (gene)


Gene Symbol:
MACROD2 Homo sapiens Homo sapiens
Full name:
MACRO domain containing 2
Synonyms:
C20orf133, C2orf133, O-acetyl-ADP-ribose deacetylase MACROD2, MACRO domain-containing protein 2, [Protein ADP-ribosylglutamate] hydrolase
Genomic Location:
Chr 20: 13924146-15981842
Description:
The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage.
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 20
20p12.1





GO Molecular Function

hydrolase activity | catalytic activity | hydrolase activity, acting on glycosyl bonds | deacetylase activity

GO Biological Process

brain development | nervous system development | cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | head development | response to stimulus | response to stress | cellular nitrogen compound metabolic process | protein modification process | purine nucleoside metabolic process | macromolecule modification | system development | nitrogen compound metabolic process | protein de-ADP-ribosylation | multicellular organism development | cellular response to DNA damage stimulus | cellular response to stress | nucleoside metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | protein metabolic process | anatomical structure development | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | cellular protein metabolic process | developmental process | cellular protein modification process | carbohydrate derivative metabolic process | heterocycle metabolic process | central nervous system development | cellular metabolic process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | microtubule organizing center | cell | nuclear lumen | nucleolus | intracellular organelle | centrosome | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoskeleton | intracellular