QuickView for MAOB (gene)
- Gene Symbol:
- MAOB
Homo sapiens - Full name:
- monoamine oxidase B
- Synonyms:
- amine oxidase [flavin-containing] B, MAO, brain, MAO, platelet, MAO-B, adrenalin oxidase, monoamine oxidase type B, tyramine oxidase
- Genomic Location:
- Chr X: 43510801-43626665
- Description:
-
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Danio rerio , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
Xp11.3
GO Molecular Function
cofactor binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | anion binding | electron transfer activity | identical protein binding | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | primary amine oxidase activity | protein binding | protein homodimerization activity | protein dimerization activity | oxidoreductase activity, acting on the CH-NH2 group of donors | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
brain development | response to lipopolysaccharide | regulation of localization | catechol-containing compound metabolic process | response to hormone | negative regulation of cellular process | response to metal ion | nervous system development | negative regulation of serotonin secretion | response to drug | reactive oxygen species metabolic process | generation of precursor metabolites and energy | response to antibiotic | phenol-containing compound metabolic process | hydrogen peroxide biosynthetic process | cellular process | organic substance catabolic process | catecholamine catabolic process | negative regulation of secretion | response to corticosterone | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of neurotransmitter transport | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | head development | response to stimulus | electron transport chain | response to alcohol | midbrain development | response to molecule of bacterial origin | regulation of dopamine metabolic process | negative regulation of transport | cofactor metabolic process | reactive oxygen species biosynthetic process | cellular biosynthetic process | dopamine metabolic process | drug catabolic process | response to ethanol | regulation of catecholamine metabolic process | regulation of neurotransmitter levels | organic hydroxy compound metabolic process | response to external biotic stimulus | system development | nitrogen compound metabolic process | negative regulation of secretion by cell | multicellular organism development | antibiotic metabolic process | electron transfer activity | dopamine catabolic process | response to ketone | response to lipid | positive regulation of cellular metabolic process | positive regulation of dopamine metabolic process | cofactor biosynthetic process | regulation of nitrogen compound metabolic process | response to corticosteroid | substantia nigra development | response to selenium ion | neurotransmitter metabolic process | biosynthetic process | negative regulation of ion transport | response to toxic substance | regulation of serotonin secretion | neurotransmitter catabolic process | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | response to bacterium | regulation of cellular metabolic process | aromatic compound catabolic process | primary amine oxidase activity | drug metabolic process | response to organic substance | catecholamine metabolic process | anatomical structure development | metabolic process | response to mineralocorticoid | oxidation-reduction process | regulation of secretion | organic substance metabolic process | oxidoreductase activity, acting on the CH-NH2 group of donors | animal organ development | organonitrogen compound catabolic process | response to organic cyclic compound | response to biotic stimulus | regulation of ion transport | developmental process | regulation of transport | response to aluminum ion | central nervous system development | hydrogen peroxide metabolic process | positive regulation of metabolic process | cellular metabolic process | oxidoreductase activity | response to steroid hormone | response to other organism | neural nucleus development | response to glucocorticoid | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | outer membrane | mitochondrial membrane | intracellular | membrane
