QuickView for MAP2 (gene)

Gene Symbol:

MAP2 Homo sapiens

Full name:

microtubule associated protein 2

Synonyms:

MAP2A, MAP2B, MAP2C, microtubule-associated protein 2, MAP-2

Genomic Location:

Chr 2: 209997016-210307079

Description:

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role...

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This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTATTAT_MIR3693P ,  ACTGTAG_MIR139 ,  AP1_C ,  TGANTCA_AP1_C ,  TAL1ALPHAE47_01 ,  TTANTCA_UNKNOWN ,  FOXJ2_02 ,  HOXA4_Q2 ,  HEN1_01 ,  POU3F2_01 ,  SMAD3_Q6 ,  TACTTGA_MIR26A_MIR26B ,  AP1_Q6 ,  TAAYNRNNTCC_UNKNOWN ,  AGGAGTG_MIR483 ,  ATGGYGGA_UNKNOWN ,  OCT1_Q6 ,  RGAANNTTC_HSF1_01 ,  NFE2_01 ,  AP1_Q6_01 ,  CATGTAA_MIR496 ,  GGATTA_PITX2_Q2 ,  GCTCTTG_MIR335 ,  AP1_01 ,  HSF1_01 ,  TST1_01 ,  AP1FJ_Q2 ,  ATTCTTT_MIR186 ,  CATRRAGC_UNKNOWN ,  NKX61_01 ,  EVI1_06 ,  CTTTAAR_UNKNOWN ,  POU1F1_Q6 ,  HSF2_01 ,  AP1_Q4 ,  OCT1_02 ,  BACH1_01 ,  AAAYRNCTG_UNKNOWN ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  WWTAAGGC_UNKNOWN ,  TEF_Q6 ,  AP1_Q2 ,  TCCATTKW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  RNTCANNRNNYNATTW_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  YWATTWNNRGCT_UNKNOWN ,  ISRE_01 ,  TGACATY_UNKNOWN ,  AP1_Q4_01 ,  TATTATA_MIR374 ,  TCF11_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-335 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-544

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Cytogenetic Map:

2q34

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