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QuickView for MAPKAP1;jsessionid=CA5DFC537F34C887BF063F93D875FEA8 (gene)


Gene Symbol:
MAPKAP1 Homo sapiens Homo sapiens
Full name:
mitogen-activated protein kinase associated protein 1
Synonyms:
JC310, MIP1, SIN1, SIN1b, SIN1g, target of rapamycin complex 2 subunit MAPKAP1, MEKK2-interacting protein 1, SAPK-interacting protein 1, TORC2 subunit MAPKAP1, mSIN1, mitogen-activated protein kinase 2-associated protein 1, ras inhibitor MGC2745, stress-activated map kinase interacting protein 1, stress-activated protein kinase-interacting 1
Genomic Location:
Chr 9: 127239494-127509334
Description:
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Schizosaccharomyces pombe Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 9
9q33.3





GO Molecular Function

kinase binding | GTPase binding | phosphatidylinositol-4,5-bisphosphate binding | protein kinase binding | enzyme binding | lipid binding | phospholipid binding | phosphatidylinositol-3,4-bisphosphate binding | Ras GTPase binding | anion binding | phosphatidylinositol bisphosphate binding | ion binding | phosphatidylinositol-3,4,5-trisphosphate binding | protein binding | phosphatidylinositol binding | phosphatidylinositol-3,5-bisphosphate binding | small GTPase binding | phosphatidic acid binding | phosphatidylinositol phosphate binding

GO Biological Process

brain development | actin filament-based process | intracellular signal transduction | actin cytoskeleton organization | negative regulation of cellular process | nervous system development | positive regulation of phosphate metabolic process | cellular process | negative regulation of signaling | TOR signaling | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | head development | response to stimulus | positive regulation of protein metabolic process | midbrain development | activation of protein kinase activity | establishment or maintenance of actin cytoskeleton polarity | system development | regulation of signal transduction | multicellular organism development | regulation of catalytic activity | regulation of phosphorylation | regulation of small GTPase mediated signal transduction | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | substantia nigra development | activation of protein kinase B activity | regulation of cellular protein metabolic process | establishment or maintenance of cell polarity | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | positive regulation of molecular function | positive regulation of protein modification process | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | animal organ development | negative regulation of small GTPase mediated signal transduction | negative regulation of Ras protein signal transduction | positive regulation of kinase activity | regulation of phosphate metabolic process | cytoskeleton organization | TORC2 signaling | regulation of cell communication | negative regulation of signal transduction | signaling | positive regulation of phosphorylation | regulation of Ras protein signal transduction | developmental process | organelle organization | establishment or maintenance of cytoskeleton polarity | central nervous system development | positive regulation of metabolic process | neural nucleus development | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | nuclear lumen | cytoplasm | intracellular organelle | Golgi apparatus | protein-containing complex | endomembrane system | nucleoplasm | plasma membrane | vesicle | TORC2 complex | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular vesicle | intracellular | membrane