QuickView for MASC (gene)
- Gene Symbol:
- Pycard
Mus musculus - Full name:
- PYD and CARD domain containing
- Synonyms:
- 9130417A21Rik, Asc, CARD5, TMS-1, TNS1, masc, apoptosis-associated speck-like protein containing a CARD, PYD and CARD domain-containing protein
- Genomic Location:
- Chr 7: 135135617-135137261
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
enzyme activator activity | cysteine-type endopeptidase activity involved in apoptotic process | tropomyosin binding | enzyme binding | peptidase activator activity | signaling receptor binding | hydrolase activity | myosin binding | cytokine receptor binding | receptor serine/threonine kinase binding | cysteine-type peptidase activity | molecular function regulator | catalytic activity | ion channel binding | protein domain specific binding | cytoskeletal protein binding | identical protein binding | peptidase activator activity involved in apoptotic process | Pyrin domain binding | cysteine-type endopeptidase activity | protein binding | protein homodimerization activity | protein dimerization activity | endopeptidase activity | enzyme regulator activity | growth factor receptor binding | protease binding | BMP receptor binding | peptidase activity | interleukin-6 receptor binding | myosin I binding
GO Biological Process
positive regulation of immune response | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | regulation of supramolecular fiber organization | regulation of interleukin-1 beta production | positive regulation of locomotion | regulation of cysteine-type endopeptidase activity | response to virus | response to cytokine | response to interleukin-1 | positive regulation of cellular component organization | response to lipopolysaccharide | negative regulation of type I interferon production | intracellular signal transduction | enzyme activator activity | positive regulation of apoptotic process | proteolysis | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | defense response to other organism | establishment of localization | regulation of autophagy | regulation of immune system process | negative regulation of cellular process | negative regulation of kinase activity | protein processing | cellular response to tumor necrosis factor | positive regulation of lymphocyte activation | defense response | intrinsic apoptotic signaling pathway in response to DNA damage | negative regulation of protein phosphorylation | positive regulation of interleukin-1 beta secretion | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | positive regulation of protein secretion | defense response to Gram-negative bacterium | positive regulation of chemokine secretion | cellular process | positive regulation of actin filament polymerization | regulation of cell motility | localization | zymogen activation | negative regulation of signaling | positive regulation of adaptive immune response | cysteine-type endopeptidase activity involved in apoptotic process | regulation of response to cytokine stimulus | positive regulation of defense response to virus by host | regulation of defense response to virus | positive regulation of release of cytochrome c from mitochondria | regulation of proteolysis | regulation of interleukin-10 secretion | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | intrinsic apoptotic signaling pathway | regulation of interferon-beta production | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of activated T cell proliferation | regulation of protein complex assembly | cellular response to molecule of bacterial origin | peptidase activator activity | positive regulation of interferon-gamma production | positive regulation of cellular protein metabolic process | positive regulation of antigen processing and presentation | cellular component organization | regulation of actin filament length | positive regulation of tumor necrosis factor production | regulation of peptide secretion | regulation of type I interferon production | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | positive regulation of interleukin-1 beta production | regulation of interleukin-8 secretion | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | interleukin-1 beta production | response to stress | leukocyte activation involved in immune response | negative regulation of protein kinase activity | positive regulation of lymphocyte proliferation | positive regulation of T cell migration | regulation of cell proliferation | positive regulation of cell-cell adhesion | positive regulation of cysteine-type endopeptidase activity | programmed cell death | positive regulation of cell activation | activation of innate immune response | positive regulation of cytokine secretion | positive regulation of proteolysis | response to molecule of bacterial origin | positive regulation of T cell activation | regulation of phagocytosis | regulation of protein transport | myeloid dendritic cell activation | negative regulation of metabolic process | regulation of cellular component size | regulation of peptide transport | regulation of cell adhesion | macropinocytosis | cysteine-type peptidase activity | molecular function regulator | positive regulation of mitochondrion organization | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | negative regulation of NF-kappaB transcription factor activity | regulation of cellular response to stress | apoptotic process | positive regulation of mononuclear cell proliferation | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | regulation of protein stability | negative regulation of phosphate metabolic process | regulation of actin cytoskeleton organization | negative regulation of catalytic activity | regulation of peptidase activity | regulation of MAPK cascade | regulation of actin filament organization | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | pinocytosis | positive regulation of lymphocyte migration | regulation of T cell activation | regulation of activated T cell proliferation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | positive regulation of antigen processing and presentation of peptide antigen via MHC class II | positive regulation of secretion | cellular response to stress | response to lipid | negative regulation of cytokine production | positive regulation of cellular metabolic process | defense response to virus | positive regulation of protein phosphorylation | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of JNK cascade | regulation of cysteine-type endopeptidase activity involved in apoptotic process | cytokine-mediated signaling pathway | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | negative regulation of protein serine/threonine kinase activity | positive regulation of protein complex assembly | vesicle-mediated transport | regulation of cellular component movement | peptidase activator activity involved in apoptotic process | positive regulation of hydrolase activity | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | positive regulation of interleukin-1 secretion | positive regulation of endopeptidase activity | protein maturation | positive regulation of chemokine production | regulation of GTPase activity | regulation of apoptotic signaling pathway | regulation of tumor necrosis factor production | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of leukocyte migration | regulation of mitochondrion organization | response to bacterium | regulation of interleukin-1 production | positive regulation of interleukin-10 secretion | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of actin filament polymerization | positive regulation of interleukin-1 production | regulation of T cell migration | inflammatory response | regulation of tumor necrosis factor-mediated signaling pathway | cell activation involved in immune response | positive regulation of cytoskeleton organization | myeloid cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | cysteine-type endopeptidase activity | regulation of locomotion | regulation of RNA metabolic process | positive regulation of transport | apoptotic signaling pathway | positive regulation of molecular function | negative regulation of interferon-beta production | regulation of cytokine secretion | cytokine production | activation of immune response | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of innate immune response | regulation of kinase activity | import into cell | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cell surface receptor signaling pathway | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | metabolic process | positive regulation of supramolecular fiber organization | negative regulation of I-kappaB kinase/NF-kappaB signaling | activation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of interleukin-1 beta secretion | regulation of adaptive immune response | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | regulation of vesicle-mediated transport | endocytosis | regulation of secretion | positive regulation of cell death | positive regulation of interleukin-6 production | immune response | positive regulation of interleukin-8 secretion | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | negative regulation of cellular protein metabolic process | gene expression | regulation of cell activation | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | positive regulation of phagocytosis | tumor necrosis factor-mediated signaling pathway | regulation of phosphate metabolic process | intrinsic apoptotic signaling pathway by p53 class mediator | positive regulation of cytokine production | regulation of JNK cascade | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | positive regulation of interleukin-10 production | negative regulation of molecular function | negative regulation of signal transduction | regulation of antigen processing and presentation | signaling | regulation of transcription, DNA-templated | endopeptidase activity | regulation of endocytosis | regulation of T cell proliferation | positive regulation of phosphorylation | enzyme regulator activity | regulation of cytokine production | regulation of endopeptidase activity | response to biotic stimulus | cellular response to interleukin-1 | regulation of chemokine production | regulation of transport | regulation of cell-cell adhesion | innate immune response | positive regulation of protein polymerization | myeloid dendritic cell activation involved in immune response | regulation of defense response to virus by host | positive regulation of metabolic process | regulation of actin filament-based process | regulation of interferon-gamma production | immune system process | peptidase activity | response to tumor necrosis factor | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | signal transduction by p53 class mediator | regulation of interleukin-6 production | regulation of inflammatory response | positive regulation of endocytosis | positive regulation of leukocyte cell-cell adhesion | activation of cysteine-type endopeptidase activity | regulation of lymphocyte migration | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | regulation of cytoskeleton organization | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to lipopolysaccharide | macromolecule metabolic process | positive regulation of interleukin-6 secretion | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
NLRP3 inflammasome complex | intracellular membrane-bounded organelle | catalytic complex | somatodendritic compartment | AIM2 inflammasome complex | cell body | protein kinase complex | cell | nuclear lumen | neuronal cell body | inflammasome complex | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | IkappaB kinase complex | protein-containing complex | endomembrane system | transferase complex | mitochondrion | NLRP1 inflammasome complex | extracellular region | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
