Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for MAT2A (gene)


Gene Symbol:
MAT2A Homo sapiens Homo sapiens
Full name:
methionine adenosyltransferase 2A
Synonyms:
MATA2, MATII, SAMS2, S-adenosylmethionine synthase isoform type-2, MAT 2, MAT-II, adoMet synthase 2, adoMet synthetase 2, methionine adenosyltransferase 2, methionine adenosyltransferase II, alpha, testicular tissue protein Li 121
Genomic Location:
Chr 2: 85619799-85625914
Description:
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
ACTGTAG_MIR139 AAGCCAT_MIR135A_MIR135B TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D E2F1_Q4_01 CAGGTCC_MIR492 MYCMAX_03 CACGTG_MYC_Q2 E2F4DP1_01 TTCNRGNNNNTTC_HSF_Q6 MAX_01
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-125 Predicted Gene Targets for miR-134 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-136 Predicted Gene Targets for miR-139 Predicted Gene Targets for miR-146 Predicted Gene Targets for miR-153 Predicted Gene Targets for miR-181 Predicted Gene Targets for miR-185 Predicted Gene Targets for miR-19
Cytogenetic Map:
chr 2
2p11.2


Transcripts Names
NM_005911



GO Molecular Function

methionine adenosyltransferase activity | cation binding | ribonucleotide binding | nucleotide binding | transferase activity, transferring alkyl or aryl (other than methyl) groups | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

protein hexamerization | response to cytokine | sulfur compound metabolic process | cellular process | S-adenosylmethionine metabolic process | one-carbon metabolic process | cellular component organization | response to stimulus | cofactor metabolic process | cellular component assembly | cellular biosynthetic process | coenzyme biosynthetic process | protein complex oligomerization | cofactor biosynthetic process | small molecule metabolic process | cellular response to cytokine stimulus | biosynthetic process | drug metabolic process | protein-containing complex assembly | response to organic substance | S-adenosylmethionine biosynthetic process | metabolic process | organic substance metabolic process | cellular response to leukemia inhibitory factor | protein heterooligomerization | cellular metabolic process | cellular response to organic substance

GO Cellular Component

catalytic complex | cell | cytoplasm | protein-containing complex | transferase complex | cytosol | intracellular | methionine adenosyltransferase complex