QuickView for MATE2-K (gene)

Gene Symbol:

SLC47A2 Homo sapiens

Full name:

solute carrier family 47 member 2

Synonyms:

MATE2, MATE2-B, MATE2-K, MATE2K, multidrug and toxin extrusion protein 2, kidney-specific H(+)/organic cation antiporter, solute carrier family 47 (multidrug and toxin extrusion), member 2

Genomic Location:

Chr 17: 19522220-19560635

Description:

This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the M...

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This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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Orthologs:

Saccharomyces cerevisiae ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

17p11.2

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