QuickView for MEC (gene)

Gene Symbol:

CCL28 Homo sapiens

Full name:

C-C motif chemokine ligand 28

Synonyms:

CCK1, MEC, SCYA28, C-C motif chemokine 28, CC chemokine CCL28, chemokine (C-C motif) ligand 28 splice variant chi, mucosae-associated epithelial chemokine, small inducible cytokine A28, small inducible cytokine subfamily A (Cys-Cys), member 28

Genomic Location:

Chr 5: 43417357-43448245

Description:

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eo...

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This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  RYTTCCTG_ETS2_B ,  GGGCGGR_SP1_Q6

Cytogenetic Map:

5p12

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