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QuickView for MGST3 (gene)


Gene Symbol:
MGST3 Homo sapiens Homo sapiens
Full name:
microsomal glutathione S-transferase 3
Synonyms:
GST-III, microsomal glutathione S-transferase 3, microsomal GST-3, microsomal GST-III, microsomal glutathione S-transferase III
Genomic Location:
Chr 1: 163867074-163891481
Description:
This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glut...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q24.1


Transcripts Names
NM_004528
XM_005245174
Protein Names
Q6ICN4
O14880
B2R592
A0A024R8Z1



GO Molecular Function

peroxidase activity | leukotriene-C4 synthase activity | glutathione transferase activity | antioxidant activity | transferase activity, transferring alkyl or aryl (other than methyl) groups | lyase activity | catalytic activity | carbon-sulfur lyase activity | protein binding | transferase activity | glutathione peroxidase activity | oxidoreductase activity, acting on peroxide as acceptor | oxidoreductase activity

GO Biological Process

leukotriene biosynthetic process | leukotriene metabolic process | sulfur compound metabolic process | peroxidase activity | glutathione derivative biosynthetic process | cellular process | cellular detoxification | antioxidant activity | xenobiotic metabolic process | icosanoid biosynthetic process | response to stimulus | cellular response to xenobiotic stimulus | cellular response to toxic substance | cellular biosynthetic process | response to nitrogen compound | nitrogen compound metabolic process | lipid metabolic process | small molecule metabolic process | biosynthetic process | response to toxic substance | response to xenobiotic stimulus | carboxylic acid metabolic process | response to organic substance | metabolic process | cellular oxidant detoxification | oxidation-reduction process | organic substance metabolic process | glutathione peroxidase activity | icosanoid metabolic process | organic acid metabolic process | detoxification | response to organonitrogen compound | oxidoreductase activity, acting on peroxide as acceptor | cellular metabolic process | oxidoreductase activity

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | nuclear envelope | membrane-bounded organelle | nucleus | organelle | intracellular | membrane