QuickView for MMP19;jsessionid=A9FD2E14C93241A69C566CE43001DB3E (gene)

Gene Symbol:

MMP19 Homo sapiens

Full name:

matrix metallopeptidase 19

Synonyms:

CODA, MMP18, RASI-1, matrix metalloproteinase-19, matrix metalloproteinase RASI, matrix metalloproteinase-18, matrix metalloproteinase-beta19

Genomic Location:

Chr 12: 54515481-54523002

Description:

This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is ac...

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This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTCTATG_MIR368 ,  TGANTCA_AP1_C ,  ACCAATC_MIR509 ,  TATAAA_TATA_01 ,  NFE2_01 ,  AP1_Q6_01 ,  TTGGGAG_MIR150 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  AP1FJ_Q2 ,  BACH2_01 ,  ATGCTGC_MIR103_MIR107 ,  HSF2_01 ,  NRF2_Q4 ,  AP1_Q4 ,  YCATTAA_UNKNOWN ,  GGCACTT_MIR519E ,  GGCCAGT_MIR193A_MIR193B ,  AP1_Q2 ,  AGGCACT_MIR5153P ,  TGASTMAGC_NFE2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-193

Cytogenetic Map:

12q13.2

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