QuickView for MOB1A (gene)

Gene Symbol:

MOB1A Homo sapiens

Full name:

MOB kinase activator 1A

Synonyms:

C2orf6, MATS1, MOB1, MOBK1B, MOBKL1B, Mob4B, MOB kinase activator 1A, MOB1 Mps One Binder homolog A, MOB1, Mps One Binder kinase activator-like 1B, mob1 alpha, mob1 homolog 1B, mps one binder kinase activator-like 1B

Genomic Location:

Chr 2: 74236719-74259503

Description:

The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variant...

View Full Description

The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  TACTTGA_MIR26A_MIR26B ,  NFY_Q6_01 ,  NFY_01

Cytogenetic Map:

2p13.1

search → result