QuickView for MPO (gene)

Gene Symbol:

MPO Homo sapiens

Full name:

myeloperoxidase

Synonyms:

myeloperoxidase

Genomic Location:

Chr 17: 53702216-53713295

Description:

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains...

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Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT4_01 ,  PU1_Q6 ,  RYTTCCTG_ETS2_B ,  AML_Q6 ,  STAT6_02 ,  MAF_Q6 ,  GGGAGGRR_MAZ_Q6 ,  AP2REP_01 ,  RGAGGAARY_PU1_Q6 ,  COREBINDINGFACTOR_Q6

Cytogenetic Map:

17q22

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