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QuickView for MRAP (gene)


Gene Symbol:
MRAP Homo sapiens Homo sapiens
Full name:
melanocortin 2 receptor accessory protein
Synonyms:
B27, C21orf61, FALP, FGD2, GCCD2, melanocortin-2 receptor accessory protein, fat cell-specific low molecular weight protein, fat tissue-specific low MW protein
Genomic Location:
Chr 21: 32585995-32608966
Description:
This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Altern...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 21
21q22.11





GO Molecular Function

type 5 melanocortin receptor binding | corticotropin hormone receptor binding | signaling receptor binding | neuropeptide receptor binding | type 3 melanocortin receptor binding | identical protein binding | protein binding | G-protein coupled receptor binding | type 4 melanocortin receptor binding | type 1 melanocortin receptor binding | melanocortin receptor binding

GO Biological Process

negative regulation of G-protein coupled receptor protein signaling pathway | protein localization to cell periphery | regulation of cellular localization | regulation of localization | negative regulation of cellular process | regulation of protein localization to membrane | localization | negative regulation of signaling | negative regulation of protein localization to plasma membrane | macromolecule localization | regulation of cellular process | regulation of cellular protein localization | positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway | cellular localization | regulation of signal transduction | negative regulation of cellular protein localization | protein localization to plasma membrane | protein localization to membrane | positive regulation of intracellular signal transduction | positive regulation of signal transduction | regulation of cAMP-mediated signaling | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of protein localization to plasma membrane | cellular protein localization | positive regulation of G-protein coupled receptor protein signaling pathway | positive regulation of cAMP-mediated signaling | regulation of cell communication | negative regulation of signal transduction | protein localization | cellular macromolecule localization | regulation of G-protein coupled receptor protein signaling pathway | negative regulation of cAMP-mediated signaling | regulation of protein localization | positive regulation of signaling | regulation of signaling

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane