QuickView for MRPL19 (gene)

Gene Symbol:

MRPL19 Homo sapiens

Full name:

mitochondrial ribosomal protein L19

Synonyms:

L19mt, MRP-L15, MRP-L19, MRPL15, RLX1, RPML15, 39S ribosomal protein L19, mitochondrial, 39S ribosomal protein L15, mitochondrial, L15mt, mitochondrial large ribosomal subunit protein bL19m

Genomic Location:

Chr 2: 75727417-75742842

Description:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Anothe...

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACTAYRNNNCCCR_UNKNOWN

Cytogenetic Map:

2p12

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