QuickView for MSRA (gene)
- Gene Symbol:
- MSRA
Homo sapiens - Full name:
- methionine sulfoxide reductase A
- Synonyms:
- PMSR, mitochondrial peptide methionine sulfoxide reductase, cytosolic methionine-S-sulfoxide reductase, peptide Met(O) reductase, peptide met (O) reductase, peptide-methionine (S)-S-oxide reductase
- Genomic Location:
- Chr 8: 9949236-10323805
- Description:
-
This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative...
- Orthologs:
- Mus musculus , Rattus norvegicus , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
8p23.1
GO Molecular Function
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | peptide-methionine (S)-S-oxide reductase activity | catalytic activity | oxidoreductase activity, acting on a sulfur group of donors | oxidoreductase activity
GO Biological Process
sulfur compound metabolic process | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | cellular process | cellular amino acid metabolic process | peptide-methionine (S)-S-oxide reductase activity | response to stimulus | response to stress | protein modification process | macromolecule modification | sulfur amino acid metabolic process | nitrogen compound metabolic process | oxidoreductase activity, acting on a sulfur group of donors | small molecule metabolic process | methionine metabolic process | response to oxidative stress | carboxylic acid metabolic process | protein metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | protein repair | organic acid metabolic process | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | oxidoreductase activity | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | actin cytoskeleton | nucleoplasm | vesicle | extracellular exosome | mitochondrion | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | cytosol | cytoskeleton | intracellular | membrane
