QuickView for MUC2 (gene)

Gene Symbol:

MUC2 Homo sapiens

Full name:

mucin 2, oligomeric mucus/gel-forming

Synonyms:

MLP, MUC-2, SMUC, mucin-2, mucin 2, intestinal/tracheal

Genomic Location:

Chr 11: 1064902-1094419

Description:

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weig...

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This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Cytogenetic Map:

11p15.5

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