QuickView for MYB (gene)

Gene Symbol:

MYB Homo sapiens

Full name:

MYB proto-oncogene, transcription factor

Synonyms:

Cmyb, c-myb, c-myb_CDS, efg, transcriptional activator Myb, oncogene AMV, proto-oncogene c-Myb, v-myb avian myeloblastosis viral oncogene homolog

Genomic Location:

Chr 6: 135544146-135582003

Description:

This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing result...

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This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  AGCYRWTTC_UNKNOWN ,  TGANTCA_AP1_C ,  TTTTGAG_MIR373 ,  CACGTG_MYC_Q2 ,  NGFIC_01 ,  CTATGCA_MIR153 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  EGR2_01 ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  AGCATTA_MIR155 ,  NFE2_01 ,  AP1_Q6_01 ,  TTGGGAG_MIR150 ,  CAGGTA_AREB6_01 ,  GGATTA_PITX2_Q2 ,  AP1_01 ,  BACH2_01 ,  ATGCTGC_MIR103_MIR107 ,  AGTCTTA_MIR499 ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  PITX2_Q2 ,  ACTGCCT_MIR34B ,  IRF_Q6 ,  RORA1_01 ,  BACH1_01 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GATA4_Q3 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  RORA2_01 ,  TGACAGNY_MEIS1_01 ,  RNTCANNRNNYNATTW_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  EGR1_01 ,  AAAGGAT_MIR501 ,  ISRE_01 ,  MMEF2_Q6 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  AP1_Q4_01 ,  EGR3_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-499

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miRNA binding sites
(Source: miRecords):

mmu-miR-150 Targeted Genes

Cytogenetic Map:

6q23.3

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