QuickView for Mimecan (gene)
- Gene Symbol:
- OGN
Homo sapiens - Full name:
- osteoglycin
- Synonyms:
- OG, OIF, SLRR3A, mimecan, corneal keratan sulfate proteoglycan, mimecan proteoglycan, osteoinductive factor
- Genomic Location:
- Chr 9: 94186070-94206758
- Description:
-
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternati...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
9q22.31
GO Molecular Function
structural molecule activity | extracellular matrix structural constituent conferring compression resistance | signaling receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | extracellular matrix structural constituent
GO Biological Process
sulfur compound metabolic process | negative regulation of cellular process | cellular process | organic substance catabolic process | carbohydrate derivative catabolic process | glycosaminoglycan catabolic process | regulation of cellular process | catabolic process | glycosaminoglycan biosynthetic process | regulation of cell proliferation | carbohydrate derivative biosynthetic process | cellular biosynthetic process | molecular function regulator | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of smooth muscle cell proliferation | small molecule metabolic process | keratan sulfate metabolic process | biosynthetic process | keratan sulfate biosynthetic process | regulation of signaling receptor activity | receptor regulator activity | growth factor activity | metabolic process | receptor ligand activity | organic substance metabolic process | keratan sulfate catabolic process | organonitrogen compound catabolic process | regulation of cell communication | organic acid metabolic process | carbohydrate derivative metabolic process | negative regulation of cell proliferation | sulfur compound catabolic process | cellular metabolic process | regulation of smooth muscle cell proliferation | regulation of signaling | glycosaminoglycan metabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | extracellular matrix | cell | vacuolar lumen | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | Golgi apparatus | endomembrane system | vacuole | vesicle | extracellular exosome | lytic vacuole | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | lysosome | extracellular space | membrane-enclosed lumen | lysosomal lumen | intracellular | Golgi lumen
