QuickView for Mn1 (gene)

Gene Symbol:

MN1 Homo sapiens

Full name:

MN1 proto-oncogene, transcriptional regulator

Synonyms:

MGCR, MGCR1, MGCR1-PEN, dJ353E16.2, transcriptional activator MN1, meningioma (disrupted in balanced translocation) 1, meningioma (translocation balanced), meningioma chromosome region 1, probable tumor suppressor protein MN1

Genomic Location:

Chr 22: 26474265-26527486

Description:

Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.

Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  SP1_01 ,  RTAAACA_FREAC2_01 ,  MZF1_01 ,  SMAD3_Q6 ,  CATTGTYY_SOX9_B1 ,  YATTNATC_UNKNOWN ,  WTGAAAT_UNKNOWN ,  YAATNRNNNYNATT_UNKNOWN ,  CDP_01 ,  CDPCR3HD_01 ,  DBP_Q6 ,  CDX2_Q5 ,  CAGCTTT_MIR320 ,  AP2_Q6_01 ,  CDPCR1_01 ,  GGGCGGR_SP1_Q6 ,  GCCNNNWTAAR_UNKNOWN ,  CEBP_Q3 ,  IK2_01 ,  WTTGKCTG_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  CDC5_01 ,  FOXM1_01 ,  GCTNWTTGK_UNKNOWN ,  AACTTT_UNKNOWN ,  TCCCCAC_MIR491 ,  CRX_Q4 ,  PAX2_02 ,  CEBPGAMMA_Q6 ,  HNF6_Q6 ,  HTF_01 ,  SP1_Q2_01 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-433-3p ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-491 ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

22q12.1

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