QuickView for Myo1c (gene)

Gene Symbol:

MYO1C Homo sapiens

Full name:

myosin IC

Synonyms:

MMI-beta, MMIb, NMI, myr2, unconventional myosin-Ic, myosin-I beta, myosin-Ic, nuclear myosin I

Genomic Location:

Chr 17: 1314230-1342751

Description:

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of thi...

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This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CEBPA_01 ,  GATA1_03 ,  RYTTCCTG_ETS2_B ,  TGANNYRGCA_TCF11MAFG_01 ,  MIF1_01 ,  SYATTGTG_UNKNOWN ,  GATA_C ,  MEIS1BHOXA9_01 ,  GATAAGR_GATA_C ,  RFX1_01 ,  GATA1_04 ,  CACCCBINDINGFACTOR_Q6 ,  YYCATTCAWW_UNKNOWN ,  TGCCTTA_MIR124A ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  CEBPB_02 ,  GATA6_01 ,  SPZ1_01 ,  POU1F1_Q6 ,  GACAGGG_MIR339 ,  GFI1_01 ,  TAATTA_CHX10_01 ,  AP2REP_01 ,  GATA1_05 ,  CAGCTG_AP4_Q5 ,  SP1_Q6_01 ,  AP4_Q5 ,  ELF1_Q6 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-204 ,  Predicted Gene Targets for miR-339 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-182

Cytogenetic Map:

17p13.3

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