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QuickView for NAPA;jsessionid=C91F7C9853544C051ED33C2A944601D7 (gene)


Gene Symbol:
NAPA Homo sapiens Homo sapiens
Full name:
NSF attachment protein alpha
Synonyms:
SNAPA, alpha-soluble NSF attachment protein, N-ethylmaleimide-sensitive factor attachment protein, alpha, alpha-SNAP
Genomic Location:
Chr 19: 52682703-52710309
Description:
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive facto...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.32-q13.33





GO Molecular Function

soluble NSF attachment protein activity | protein-containing complex binding | syntaxin binding | protein binding | SNARE binding

GO Biological Process

brain development | positive regulation of ATPase activity | regulation of cellular localization | regulation of localization | establishment of localization | membrane fusion | cell differentiation | nervous system development | neurogenesis | generation of neurons | membrane organization | intracellular transport | SNARE complex disassembly | cellular process | establishment of organelle localization | intra-Golgi vesicle-mediated transport | localization | protein transport | chemical synaptic transmission | macromolecule localization | positive regulation of catalytic activity | establishment of localization in cell | vesicle targeting, to, from or within Golgi | regulation of cellular process | regulation of protein complex assembly | organelle localization | cellular component organization | head development | COPII-coated vesicle budding | regulation of ATPase activity | intracellular protein transport | cellular localization | cellular component assembly | modulation of chemical synaptic transmission | vesicle targeting | cell-cell signaling | regulation of intracellular transport | regulation of neurotransmitter levels | system development | multicellular organism development | retrograde vesicle-mediated transport, Golgi to ER | regulation of synaptic vesicle exocytosis | regulation of catalytic activity | vesicle coating | organic substance transport | synaptic signaling | peptide transport | vesicle-mediated transport | positive regulation of hydrolase activity | Golgi vesicle budding | synaptic transmission, glutamatergic | establishment of vesicle localization | regulation of synaptic vesicle transport | cell communication | apical protein localization | cellular protein complex disassembly | Golgi vesicle transport | positive regulation of molecular function | neuron differentiation | protein-containing complex assembly | regulation of exocytosis | anatomical structure development | cellular protein localization | amide transport | regulation of vesicle-mediated transport | regulation of secretion | animal organ development | establishment of protein localization | vesicle organization | regulation of regulated secretory pathway | vesicle budding from membrane | regulation of cell communication | ER to Golgi vesicle-mediated transport | signaling | protein localization | protein-containing complex disassembly | cellular macromolecule localization | developmental process | organelle organization | COPII vesicle coating | regulation of transport | regulation of calcium ion-dependent exocytosis | central nervous system development | vesicle localization | regulation of synaptic vesicle priming | regulation of cellular component organization | regulation of signaling | regulation of neurotransmitter secretion | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | Golgi apparatus | protein-containing complex | endomembrane system | plasma membrane | vacuole | vesicle | extracellular exosome | SNARE complex | Golgi membrane | extracellular region | membrane-bounded organelle | synaptobrevin 2-SNAP-25-syntaxin-1a complex | extracellular vesicle | organelle | extracellular space | cell periphery | cytosol | intracellular | myelin sheath | membrane | vacuolar membrane