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QuickView for NDEL1;jsessionid=993FE55E2C76CD0233A0C9223C25DC3D (gene)


Gene Symbol:
NDEL1 Homo sapiens Homo sapiens
Full name:
nudE neurodevelopment protein 1 like 1
Synonyms:
EOPA, MITAP1, NDE1L1, NDE2, NUDEL, nuclear distribution protein nudE-like 1, endooligopeptidase A, mitosin-associated protein 1, mitosin-associated protein MITAP1, nudE nuclear distribution E homolog-like 1, nudE nuclear distribution gene E homolog-like 1, protein Nudel
Genomic Location:
Chr 17: 8279904-8312206
Description:
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromo...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17p13.1





GO Molecular Function

alpha-tubulin binding | protein-containing complex binding | hydrolase activity | catalytic activity | beta-tubulin binding | cytoskeletal protein binding | identical protein binding | oligopeptidase activity | protein binding | microtubule binding | tubulin binding | peptidase activity

GO Biological Process

lysosome localization | brain development | cell morphogenesis | nucleus organization | activation of GTPase activity | regulation of intracellular protein transport | microtubule-based transport | microtubule cytoskeleton organization involved in mitosis | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cellular localization | positive regulation of axon regeneration | proteolysis | regulation of cell development | regulation of localization | establishment of localization | response to hormone | neuron migration | positive regulation of developmental process | microtubule cytoskeleton organization | establishment of mitotic spindle orientation | cell differentiation | nervous system development | cell part morphogenesis | positive regulation of axonogenesis | neurogenesis | generation of neurons | membrane organization | vesicle cytoskeletal trafficking | intracellular transport | microtubule-based process | positive regulation of GTPase activity | neuron projection extension | cellular process | establishment of organelle localization | centrosome separation | central nervous system neuron axonogenesis | localization | cell projection morphogenesis | forebrain cell migration | developmental growth | neuron development | central nervous system neuron differentiation | positive regulation of ruffle assembly | endomembrane system organization | microtubule organizing center organization | inner cell mass cell proliferation | establishment of mitotic spindle localization | positive regulation of catalytic activity | membrane disassembly | regulation of neuron projection development | establishment of localization in cell | response to peptide hormone | regulation of cell differentiation | cytoskeleton-dependent intracellular transport | regulation of microtubule motor activity | regulation of cellular process | microtubule polymerization | positive regulation of cell growth | organelle localization | microtubule nucleation | cellular response to organonitrogen compound | establishment of cell polarity | cellular component organization | establishment of chromosome localization | head development | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | retrograde axonal transport | chromosome segregation | organelle transport along microtubule | establishment of spindle localization | response to peptide | telencephalon cell migration | supramolecular fiber organization | microtubule-based movement | cellular localization | neurofilament cytoskeleton organization | regulation of neuron projection regeneration | nuclear envelope organization | regulation of protein transport | regulation of cellular component size | cellular component assembly | regulation of axon extension | regulation of peptide transport | embryo development | regulation of intracellular transport | regulation of cellular response to stress | locomotion | response to nitrogen compound | central nervous system neuron development | cellular response to hormone stimulus | regulation of cell projection assembly | system development | positive regulation of response to wounding | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | cell migration | cellular response to peptide hormone stimulus | regulation of axonogenesis | spindle localization | cellular response to insulin stimulus | regulation of catalytic activity | positive regulation of neuron projection regeneration | telencephalon development | regulation of neuron differentiation | axon development | cellular response to peptide | cell cycle | insulin receptor signaling pathway | enzyme linked receptor protein signaling pathway | positive regulation of cell projection organization | protein polymerization | axonogenesis | positive regulation of hydrolase activity | positive regulation of cell differentiation | establishment of spindle orientation | establishment of vesicle localization | cell proliferation | cellular protein-containing complex assembly | regulation of GTPase activity | cerebral cortex cell migration | cell morphogenesis involved in differentiation | establishment or maintenance of cell polarity | mitotic centrosome separation | chordate embryonic development | nuclear envelope disassembly | cell communication | centrosome localization | embryo development ending in birth or egg hatching | cerebral cortex development | oligopeptidase activity | positive regulation of molecular function | positive regulation of axon extension | neuron differentiation | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of establishment of protein localization | regulation of growth | response to organic substance | centrosome cycle | response to insulin | anatomical structure development | developmental growth involved in morphogenesis | mitotic cell cycle | cell surface receptor signaling pathway | positive regulation of neurogenesis | nuclear division | cell projection organization | metabolic process | positive regulation of cell development | transport along microtubule | microtubule organizing center localization | intermediate filament-based process | regulation of ruffle assembly | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | animal organ development | cerebral cortex radially oriented cell migration | forebrain development | pallium development | cytoskeleton organization | mitotic nuclear division | microtubule polymerization or depolymerization | blastocyst development | regulation of axon regeneration | regulation of response to wounding | axo-dendritic transport | positive regulation of developmental growth | signaling | positive regulation of growth | cell development | regulation of developmental growth | regulation of cell size | anatomical structure morphogenesis | positive regulation of plasma membrane bounded cell projection assembly | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | regulation of cell growth | blastocyst growth | vesicle transport along microtubule | regulation of transport | intermediate filament cytoskeleton organization | developmental cell growth | response to organonitrogen compound | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | in utero embryonic development | vesicle localization | positive regulation of neuron differentiation | regulation of cell projection organization | peptidase activity | cellular response to organic substance | regulation of protein localization | positive regulation of cell morphogenesis involved in differentiation | regulation of cellular component organization | axonal transport | signal transduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

supramolecular fiber | exocytic vesicle | neurofilament cytoskeleton | chromosome | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | microtubule associated complex | microtubule organizing center | central region of growth cone | chromosome, centromeric region | cytoplasmic vesicle | condensed chromosome, centromeric region | cell body | cell | neuronal cell body | distal axon | kinetochore | microtubule | cytoplasm | spindle | intracellular organelle | intermediate filament cytoskeleton | presynapse | centrosome | kinesin complex | protein-containing complex | cell projection | secretory vesicle | endomembrane system | plasma membrane bounded cell projection cytoplasm | nuclear envelope | axon hillock | cell leading edge | vesicle | transport vesicle | condensed chromosome kinetochore | microtubule cytoskeleton | cytoplasmic region | site of polarized growth | synaptic vesicle | membrane-bounded organelle | nucleus | organelle | axon cytoplasm | axon | growth cone | cytosol | intracellular vesicle | cytoskeleton | intracellular | supramolecular complex | condensed chromosome