QuickView for NDUFA2 (gene)

Gene Symbol:

NDUFA2 Homo sapiens

Full name:

NADH:ubiquinone oxidoreductase subunit A2

Synonyms:

B8, CD14, CIB8, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa, NADH-ubiquinone oxidoreductase subunit CI-B8, complex I B8 subunit

Genomic Location:

Chr 5: 140005142-140007424

Description:

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene a...

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The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-421

Cytogenetic Map:

5q31.3

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