QuickView for NDUFA6 (gene)
- Gene Symbol:
- NDUFA6
Homo sapiens - Full name:
- NADH:ubiquinone oxidoreductase subunit A6
- Synonyms:
- B14, CI-B14, LYRM6, NADHB14, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6, Complex I-B14, LYR motif-containing protein 6, NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 6, NADH-ubiquinone oxidoreductase B14 subunit
- Genomic Location:
- Chr 22: 40811476-40816834
- Description:
-
This gene encodes a member of the LYR family of proteins that contain a highly conserved tripeptide (LYR) motif near the N-terminus. The encoded protein is an accessory subunit of NADH: ubiquinone oxidorerductase (Complex I), which is the largest enzyme of the mitochondrial membrane respiratory chain. Complex I functions in electron transfer from N...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
22q13.2
GO Molecular Function
oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | catalytic activity | NADH dehydrogenase activity | NADH dehydrogenase (ubiquinone) activity | oxidoreductase activity
GO Biological Process
purine ribonucleotide metabolic process | oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | generation of precursor metabolites and energy | cellular process | nucleotide metabolic process | ATP synthesis coupled electron transport | cellular respiration | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | mitochondrial respiratory chain complex assembly | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | purine nucleotide metabolic process | response to stress | mitochondrial respiratory chain complex I assembly | electron transport chain | cellular nitrogen compound metabolic process | cellular component assembly | mitochondrion organization | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | NADH dehydrogenase complex assembly | small molecule metabolic process | response to oxidative stress | nucleobase-containing small molecule metabolic process | phosphorylation | cellular protein-containing complex assembly | phosphate-containing compound metabolic process | mitochondrial ATP synthesis coupled electron transport | drug metabolic process | protein-containing complex assembly | NADH dehydrogenase activity | metabolic process | oxidation-reduction process | oxidative phosphorylation | nucleobase-containing compound metabolic process | organic substance metabolic process | NADH dehydrogenase (ubiquinone) activity | energy derivation by oxidation of organic compounds | organelle organization | carbohydrate derivative metabolic process | mitochondrial electron transport, NADH to ubiquinone | heterocycle metabolic process | cellular metabolic process | ATP metabolic process | oxidoreductase activity | respiratory electron transport chain
GO Cellular Component
organelle inner membrane | intracellular membrane-bounded organelle | catalytic complex | mitochondrial inner membrane | organelle membrane | cell | oxidoreductase complex | mitochondrial respiratory chain complex I | cytoplasm | respiratory chain complex I | intracellular organelle | protein-containing complex | mitochondrial respiratory chain | respiratory chain | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane
