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QuickView for NDUFA8;jsessionid=8D6482F604460A254794A0AD8A49B9B2 (gene)


Gene Symbol:
NDUFA8 Homo sapiens Homo sapiens
Full name:
NADH:ubiquinone oxidoreductase subunit A8
Synonyms:
CI-19KD, CI-PGIV, PGIV, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa, NADH-ubiquinone oxidoreductase 19 kDa subunit, NADH:ubiquinone oxidoreductase PGIV subunit, complex I-19kD, complex I-PGIV
Genomic Location:
Chr 9: 123946158-123961919
Description:
The protein encoded by this gene belongs to the complex I 19 kDa subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 9
9q33.2


Transcripts Names
NM_014222
NM_001318195
Protein Names
Q9Y6N0
P51970
B1AM93
B7Z768



GO Molecular Function

oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | protein-containing complex binding | catalytic activity | NADH dehydrogenase activity | NADH dehydrogenase (ubiquinone) activity | oxidoreductase activity

GO Biological Process

purine ribonucleotide metabolic process | oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | generation of precursor metabolites and energy | cellular process | nucleotide metabolic process | ATP synthesis coupled electron transport | cellular respiration | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | mitochondrial respiratory chain complex assembly | cellular aromatic compound metabolic process | cellular component organization | purine nucleotide metabolic process | mitochondrial respiratory chain complex I assembly | electron transport chain | cellular nitrogen compound metabolic process | cellular component assembly | mitochondrion organization | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | NADH dehydrogenase complex assembly | small molecule metabolic process | nucleobase-containing small molecule metabolic process | phosphorylation | cellular protein-containing complex assembly | phosphate-containing compound metabolic process | mitochondrial ATP synthesis coupled electron transport | drug metabolic process | protein-containing complex assembly | NADH dehydrogenase activity | metabolic process | oxidation-reduction process | oxidative phosphorylation | nucleobase-containing compound metabolic process | organic substance metabolic process | NADH dehydrogenase (ubiquinone) activity | energy derivation by oxidation of organic compounds | organelle organization | carbohydrate derivative metabolic process | mitochondrial electron transport, NADH to ubiquinone | heterocycle metabolic process | cellular metabolic process | ATP metabolic process | oxidoreductase activity | respiratory electron transport chain

GO Cellular Component

mitochondrial intermembrane space | organelle inner membrane | intracellular membrane-bounded organelle | catalytic complex | mitochondrial inner membrane | organelle membrane | cell | oxidoreductase complex | mitochondrial respiratory chain complex I | cytoplasm | respiratory chain complex I | intracellular organelle | protein-containing complex | mitochondrial respiratory chain | respiratory chain | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | membrane-enclosed lumen | mitochondrial membrane | intracellular | membrane