QuickView for NDUFS7 (gene)

Gene Symbol:

NDUFS7 Homo sapiens

Full name:

NADH:ubiquinone oxidoreductase core subunit S7

Synonyms:

CI-20, CI-20KD, MY017, PSST, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase), NADH-coenzyme Q reductase, NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH:ubiquinone oxidoreductase PSST subunit, PSST subunit, complex I 20kDa subunit, complex I, mitochondrial respiratory chain, 20-KD subunit, complex I-20kD

Genomic Location:

Chr 19: 1334906-1346581

Description:

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquino...

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This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

19p13.3

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