QuickView for NEO1;jsessionid=452333ADFD07666B587F4F86A86F2139 (gene)

Gene Symbol:

NEO1 Homo sapiens

Full name:

neogenin 1

Synonyms:

IGDCC2, NGN, NTN1R2, neogenin, immunoglobulin superfamily DCC subclass member 2, neogenin homolog 1

Genomic Location:

Chr 15: 71131928-71384599

Description:

This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be inv...

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This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGTG_MIR128A_MIR128B ,  OCT1_07 ,  RTAAACA_FREAC2_01 ,  HNF3ALPHA_Q6 ,  TTANTCA_UNKNOWN ,  FOXJ2_02 ,  FOX_Q2 ,  HOXA4_Q2 ,  AP3_Q6 ,  FOXO4_01 ,  AAAYWAACM_HFH4_01 ,  FOXD3_01 ,  HFH1_01 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  CEBP_Q2_01 ,  IPF1_Q4 ,  VDR_Q6 ,  AP2GAMMA_01 ,  CAGCACT_MIR5123P ,  STAT6_01 ,  HNF1_C ,  CTTTGA_LEF1_Q2 ,  NKX22_01 ,  ACTGTGA_MIR27A_MIR27B ,  GGGAGGRR_MAZ_Q6 ,  AR_Q6 ,  CEBP_Q2 ,  CEBPDELTA_Q6 ,  SOX9_B1 ,  TITF1_Q3 ,  CEBP_01 ,  CDX2_Q5 ,  LHX3_01 ,  AP2_Q6_01 ,  SP3_Q3 ,  FOXJ2_01 ,  STAT5A_03 ,  OCT1_03 ,  CCCNNGGGAR_OLF1_01 ,  S8_01 ,  NKX25_02 ,  HFH4_01 ,  YCATTAA_UNKNOWN ,  RORA1_01 ,  EN1_01 ,  CHX10_01 ,  POU3F2_02 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  GATA1_05 ,  TEF_Q6 ,  YTAATTAA_LHX3_01 ,  CTTTGT_LEF1_Q2 ,  CRX_Q4 ,  TCF1P_Q6 ,  TATTATA_MIR374 ,  HOX13_01 ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-328 ,  Predicted Gene Targets for miR-342 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-374

Cytogenetic Map:

15q24.1

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