QuickView for NK6 homeobox 1 (gene)

Gene Symbol:

NKX6-1 Homo sapiens

Full name:

NK6 homeobox 1

Synonyms:

NKX6.1, NKX6A, homeobox protein Nkx-6.1, NK homeo box, family 6, member A, NK homeobox, family 6, A, NK6 transcription factor homolog A, NK6 transcription factor related, locus 1, homeobox protein NK-6 homolog A

Genomic Location:

Chr 4: 85633460-85638411

Description:

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SRF_Q6 ,  CTTTGA_LEF1_Q2 ,  GGATTA_PITX2_Q2 ,  NFY_Q6_01 ,  CDX2_Q5 ,  LHX3_01 ,  TATA_C ,  CREB_02 ,  AREB6_01 ,  NFY_01 ,  CTTTAAR_UNKNOWN ,  TAATTA_CHX10_01 ,  WTTGKCTG_UNKNOWN ,  YTAATTAA_LHX3_01 ,  T3R_Q6 ,  RYAAAKNNNNNNTTGW_UNKNOWN ,  AACTTT_UNKNOWN ,  CRX_Q4 ,  ER_Q6 ,  CCAWWNAAGG_SRF_Q4

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Cytogenetic Map:

4q21.23

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