QuickView for NNT (gene)

Gene Symbol:

NNT Homo sapiens

Full name:

nicotinamide nucleotide transhydrogenase

Synonyms:

GCCD4, NAD(P) transhydrogenase, mitochondrial, pyridine nucleotide transhydrogenase

Genomic Location:

Chr 5: 43638548-43741425

Description:

This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The res...

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This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  TTANTCA_UNKNOWN ,  SYATTGTG_UNKNOWN ,  CTAWWWATA_RSRFC4_Q2 ,  TATAAA_TATA_01 ,  GGGCGGR_SP1_Q6 ,  FOXO1_01 ,  FREAC2_01 ,  TTGTTT_FOXO4_01 ,  TATA_01 ,  TBP_01 ,  PAX3_B ,  ER_Q6_01

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Cytogenetic Map:

5p12

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