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QuickView for NR2F2 (gene)


Gene Symbol:
NR2F2 Homo sapiens Homo sapiens
Full name:
nuclear receptor subfamily 2 group F member 2
Synonyms:
ARP1, CHTD4, COUPTFB, COUPTFII, NF-E3, NR2F1, SVP40, TFCOUP2, COUP transcription factor 2, ADP-ribosylation factor related protein 1, COUP transcription factor II, apolipoprotein A-I regulatory protein 1, apolipoprotein AI regulatory protein 1, chicken ovalbumin upstream promoter transcription factor 2, chicken ovalbumin upstream promoter-transcription factor I
Genomic Location:
Chr 15: 94674950-94683048
Description:
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
SP1_01 HNF4ALPHA_Q6 GTATTAT_MIR3693P CEBPA_01 NFAT_Q6 OCT1_01 SRF_Q6 ZF5_01 SMAD3_Q6 GCANCTGNY_MYOD_Q6
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 15
15q26.2





GO Molecular Function

sequence-specific DNA binding | isoprenoid binding | retinoid binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | carboxylic acid binding | nucleic acid binding | lipid binding | steroid hormone receptor activity | anion binding | DNA binding | signaling receptor activity | transcription corepressor activity | identical protein binding | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | zinc ion binding | DNA-binding transcription factor activity | protein dimerization activity | transition metal ion binding | retinoic acid binding | transcription coregulator activity | organic acid binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | negative regulation of phosphorylation | brain development | limb development | radial pattern formation | lymphatic endothelial cell fate commitment | positive regulation of macromolecule biosynthetic process | cell motility | developmental process involved in reproduction | muscle tissue development | regulation of localization | response to hormone | neuron migration | negative regulation of cellular process | negative regulation of kinase activity | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | endothelial cell differentiation | maternal placenta development | nervous system development | negative regulation of protein phosphorylation | neurogenesis | generation of neurons | hormone-mediated signaling pathway | blood vessel morphogenesis | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | nuclear receptor activity | regulation of cell motility | localization | reproductive system development | response to estradiol | female pregnancy | transcription factor activity, direct ligand regulated sequence-specific DNA binding | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | negative regulation of cellular metabolic process | tissue development | muscle structure development | skeletal muscle organ development | negative regulation of cell motility | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | head development | response to stimulus | positive regulation of blood pressure | vasculature development | regulation of transcription involved in lymphatic endothelial cell fate commitment | negative regulation of protein kinase activity | trophoblast giant cell differentiation | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | reproduction | cardiovascular system development | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | blood circulation | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | embryo development | embryonic placenta development | blood vessel development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | locomotion | cellular response to hormone stimulus | epithelial cell fate commitment | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | reproductive process | endothelium development | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | cell migration | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | lymph vessel development | regulation of phosphorylation | regulation of gene expression | response to lipid | regulation of blood pressure | negative regulation of cyclin-dependent protein serine/threonine kinase activity | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | placenta blood vessel development | regulation of cell migration | negative regulation of protein serine/threonine kinase activity | transcription corepressor activity | regulation of cellular component movement | regulation of transcription by RNA polymerase II | regulation of endothelial cell migration | negative regulation of epithelial cell migration | biosynthetic process | cell differentiation involved in embryonic placenta development | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | fertilization | chordate embryonic development | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | positive regulation of systemic arterial blood pressure | multicellular organism reproduction | maternal process involved in female pregnancy | negative regulation of cyclin-dependent protein kinase activity | negative regulation of epithelial cell proliferation | DNA-binding transcription factor activity | regionalization | response to organic substance | regulation of kinase activity | anatomical structure development | lymphatic endothelial cell differentiation | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | negative regulation of endothelial cell proliferation | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of endothelial cell proliferation | forebrain development | negative regulation of cellular protein metabolic process | gene expression | negative regulation of cellular component movement | regulation of phosphate metabolic process | cellular response to steroid hormone stimulus | regulation of transcription involved in cell fate commitment | transcription, DNA-templated | intracellular receptor signaling pathway | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of epithelial cell migration | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of epithelial cell proliferation | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | negative regulation of endothelial cell migration | transcription coregulator activity | epithelial cell differentiation | heterocycle metabolic process | central nervous system development | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | placenta development | cellular response to organic substance | response to steroid hormone | circulatory system development | negative regulation of locomotion | sexual reproduction | muscle organ development | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular