QuickView for NSP5 (gene)

Gene Symbol:

SPECC1 Homo sapiens

Full name:

sperm antigen with calponin homology and coiled-coil domains 1

Synonyms:

CYTSB, HCMOGT-1, HCMOGT1, NSP, cytospin-B, NSP5, cytokinesis and spindle organization B, nuclear structure protein 5, sperm antigen HCMOGT-1, sperm antigen with calponin-like and coiled coil domains 1, structure protein NSP5a3a, structure protein NSP5a3b, structure protein NSP5b3a, structure protein NSP5b3b

Genomic Location:

Chr 17: 19930927-20158660

Description:

The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transc...

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The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCATTTG_MIR105 ,  SMAD3_Q6 ,  CATTGTYY_SOX9_B1 ,  HEB_Q6 ,  WGGAATGY_TEF1_Q6 ,  RGAGGAARY_PU1_Q6 ,  CAGCTG_AP4_Q5

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-31

Cytogenetic Map:

17p11.2

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