QuickView for NUDT6 (gene)

Gene Symbol:

NUDT6 Homo sapiens

Full name:

nudix hydrolase 6

Synonyms:

ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1, nucleoside diphosphate-linked moiety X motif 6, antisense basic fibroblast growth factor, nudix (nucleoside diphosphate linked moiety X)-type motif 6

Genomic Location:

Chr 4: 124033249-124063573

Description:

This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antipro...

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This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_07 ,  YATGNWAAT_OCT_C ,  SCGGAAGY_ELK1_02

Cytogenetic Map:

4q28.1

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