QuickView for Nardilysin (gene)

Gene Symbol:

NRDC Homo sapiens

Full name:

nardilysin convertase

Synonyms:

NRD1, hNRD1, hNRD2, nardilysin, NRD convertase, nardilysin (N-arginine dibasic convertase)

Genomic Location:

Chr 1: 52027452-52117197

Description:

This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding differ...

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This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  TGANTCA_AP1_C ,  NGFIC_01 ,  VDR_Q6 ,  CREB_Q3 ,  NFE2_01 ,  AP1_Q6_01 ,  NFY_Q6_01 ,  AP4_01 ,  EGR_Q6 ,  GGGCGGR_SP1_Q6 ,  ACTGCAG_MIR173P ,  RNGTGGGC_UNKNOWN ,  CETS1P54_01 ,  SCGGAAGY_ELK1_02 ,  PAX4_01 ,  TGASTMAGC_NFE2_01

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Cytogenetic Map:

1p32.3

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