QuickView for Nop58 (gene)
- Gene Symbol:
- NOP58
Homo sapiens - Full name:
- NOP58 ribonucleoprotein
- Synonyms:
- HSPC120, NOP5, NOP5/NOP58, nucleolar protein 58, NOP58 ribonucleoprotein homolog, nucleolar protein 5, nucleolar protein NOP5/NOP58
- Genomic Location:
- Chr 2: 202838760-202876629
- Description:
-
The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Danio rerio , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
ARNT_01 , MYCMAX_03 , CACGTG_MYC_Q2 , TTCNRGNNNNTTC_HSF_Q6 , MAX_01 , CTTTGTA_MIR524 , GTGACGY_E4F1_Q6 , MYCMAX_01 , USF_01 , USF_02
- Cytogenetic Map:
-
2q33.1
GO Molecular Function
snoRNA binding | enzyme binding | nucleic acid binding | TFIID-class transcription factor binding | ATPase binding | organic cyclic compound binding | protein binding | transcription factor binding | RNA polymerase II transcription factor binding | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | RNA processing | cellular process | localization | macromolecule localization | ribosome biogenesis | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | ncRNA processing | cellular nitrogen compound metabolic process | nitrogen compound metabolic process | rRNA metabolic process | rRNA processing | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | ncRNA metabolic process | snoRNA localization | heterocycle metabolic process | ribonucleoprotein complex biogenesis | cellular metabolic process | RNA localization | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | fibrillar center | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | Cajal body | nuclear body | protein-containing complex | pre-snoRNP complex | nucleoplasm | ribonucleoprotein complex | membrane-bounded organelle | preribosome | box C/D snoRNP complex | nucleus | organelle | membrane-enclosed lumen | small-subunit processome | cytosol | intracellular | membrane | small nucleolar ribonucleoprotein complex
