QuickView for Ntsr1 (gene)
- Gene Symbol:
- NTSR1
Homo sapiens - Full name:
- neurotensin receptor 1
- Synonyms:
- NTR, neurotensin receptor type 1, NT-R-1, NTR1, NTRH, high-affinity levocabastine-insensitive neurotensin receptor, neurotensin receptor 1 (high affinity)
- Genomic Location:
- Chr 20: 60810634-60864568
- Description:
-
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
20q13.33
GO Molecular Function
transmembrane signaling receptor activity | G-protein coupled receptor activity | neuropeptide receptor activity | protein N-terminus binding | signaling receptor activity | identical protein binding | protein heterodimerization activity | G-protein coupled neurotensin receptor activity | protein binding | protein homodimerization activity | protein dimerization activity | peptide receptor activity | G-protein coupled peptide receptor activity
GO Biological Process
positive regulation of release of sequestered calcium ion into cytosol | detection of stimulus | positive regulation of ion transmembrane transporter activity | regulation of cellular localization | positive regulation of apoptotic process | regulation of localization | L-amino acid transport | regulation of carbohydrate metabolic process | regulation of programmed cell death | establishment of localization | negative regulation of cellular process | response to drug | organophosphate catabolic process | regulation of inositol phosphate biosynthetic process | cellular chemical homeostasis | polyol metabolic process | positive regulation of phosphate metabolic process | positive regulation of cation channel activity | regulation of lipid transport | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | neuropeptide signaling pathway | organic substance catabolic process | L-glutamate import across plasma membrane | localization | cellular homeostasis | regulation of gamma-aminobutyric acid secretion | modulation of inhibitory postsynaptic potential | positive regulation of synaptic transmission | regulation of respiratory gaseous exchange | chemical synaptic transmission | dicarboxylic acid transport | anion transport | learning | negative regulation of apoptotic process | regulation of neurological system process | inositol phosphate catabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | regulation of cytosolic calcium ion concentration | positive regulation of arachidonic acid secretion | calcium ion homeostasis | G-protein coupled receptor activity | response to stimulus | positive regulation of cation transmembrane transport | alcohol metabolic process | multicellular organismal homeostasis | sensory perception of temperature stimulus | response to temperature stimulus | neuropeptide receptor activity | negative regulation of transport | blood circulation | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | cell-cell signaling | carboxylic acid transmembrane transport | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | metal ion homeostasis | negative regulation of blood pressure | detection of temperature stimulus involved in sensory perception | regulation of membrane potential | detection of abiotic stimulus | regulation of neurotransmitter levels | organic hydroxy compound metabolic process | regulation of calcium ion transport into cytosol | D-aspartate import across plasma membrane | alcohol catabolic process | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | positive regulation of icosanoid secretion | phosphorus metabolic process | learning or memory | positive regulation of glutamate secretion | positive regulation of inhibitory postsynaptic potential | ion transmembrane transport | regulation of sensory perception of pain | amino acid import | positive regulation of secretion | organic substance transport | response to lipid | nervous system process | regulation of blood pressure | synaptic signaling | organophosphate metabolic process | regulation of membrane depolarization | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | cellular ion homeostasis | adult locomotory behavior | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | small molecule metabolic process | negative regulation of release of sequestered calcium ion into cytosol | organic acid transport | cognition | regulation of release of sequestered calcium ion into cytosol | negative regulation of ion transmembrane transport | locomotory behavior | sensory perception of pain | organic anion transport | negative regulation of ion transport | regulation of calcium ion transmembrane transport | regulation of glutamate secretion | detection of temperature stimulus involved in sensory perception of pain | positive regulation of lipid localization | cation homeostasis | phosphate-containing compound metabolic process | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of transporter activity | positive regulation of sequestering of calcium ion | negative regulation of calcium ion transport | G-protein coupled neurotensin receptor activity | positive regulation of inositol phosphate biosynthetic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of transport | negative regulation of calcium ion transport into cytosol | amino acid transport | positive regulation of molecular function | response to organic substance | import into cell | detection of stimulus involved in sensory perception | amino acid transmembrane transport | anion transmembrane transport | organic acid transmembrane transport | L-alpha-amino acid transmembrane transport | metabolic process | neurotransmitter uptake | negative regulation of programmed cell death | L-glutamate transmembrane transport | chemical homeostasis | regulation of secretion | behavior | positive regulation of cell death | regulation of arachidonic acid secretion | organic substance metabolic process | regulation of sequestering of calcium ion | positive regulation of amino acid transport | positive regulation of ion transport | positive regulation of programmed cell death | ion homeostasis | regulation of phosphate metabolic process | regulation of ion transmembrane transport | L-glutamate import | positive regulation of organic acid transport | positive regulation of gamma-aminobutyric acid secretion | temperature homeostasis | drug transport | adult behavior | sensory perception | positive regulation of carbohydrate metabolic process | regulation of action potential | regulation of cell communication | transmembrane transport | signaling | G-protein coupled peptide receptor activity | negative regulation of systemic arterial blood pressure | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | drug transmembrane transport | carboxylic acid transport | positive regulation of calcium ion transport into cytosol | regulation of ion transport | positive regulation of anion transport | regulation of calcium ion transport | detection of temperature stimulus | regulation of transport | neurotransmitter transport | regulation of fatty acid transport | regulation of cation channel activity | cellular metal ion homeostasis | regulation of anion transport | positive regulation of metabolic process | ion transport | positive regulation of lipid transport | cellular metabolic process | regulation of cell death | negative regulation of cell death | divalent inorganic cation homeostasis | positive regulation of calcium ion transport | positive regulation of signaling | inositol phosphate metabolic process | signal transduction | regulation of signaling | positive regulation of fatty acid transport | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
dendritic spine | integral component of membrane | cytoplasmic side of plasma membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | symmetric synapse | cell body | cell | cytoplasmic side of membrane | neuronal cell body | distal axon | intrinsic component of membrane | terminal bouton | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | dendritic tree | presynapse | Golgi apparatus | cell projection | endomembrane system | neuron spine | postsynapse | plasma membrane | perikaryon | membrane raft | mitochondrion | integral component of plasma membrane | membrane-bounded organelle | dendritic shaft | organelle | axon terminus | cell periphery | axon | neuron projection terminus | cell surface | intracellular | membrane | intrinsic component of plasma membrane
