QuickView for Nucleoplasmin core domain (biogroup)

Description:: This entry represents the core structural domain for the nucleoplasmin (Np) family of histone chaperone proteins. This core domain is formed by an 8-stranded beta barrel.The three branches of the Np family, including nucleophosmin (NO38/B23), nucleoplasmin (Np), and nucleoplasmin-like proteins (NLP), bind core histones and assemble nucleosomes in vitro assays. Even though they have different histone preferences, it has been suggested that Np family members may share a general mechanism for binding histones.

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