QuickView for Oat (gene)

Gene Symbol:

OAT Homo sapiens

Full name:

ornithine aminotransferase

Synonyms:

GACR, HOGA, OATASE, OKT, ornithine aminotransferase, mitochondrial, gyrate atrophy, ornithine delta-aminotransferase, ornithine-oxo-acid aminotransferase, testicular tissue protein Li 130

Genomic Location:

Chr 10: 126075862-126097441

Description:

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively s...

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This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  TGACCTY_ERR1_Q2 ,  GGGCGGR_SP1_Q6 ,  TGTTTGY_HNF3_Q6

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

10q26.13

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