QuickView for Opa3 (gene)

Gene Symbol:

OPA3 Homo sapiens

Full name:

OPA3, outer mitochondrial membrane lipid metabolism regulator

Synonyms:

MGA3, optic atrophy 3 protein, Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus'), optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

Genomic Location:

Chr 19: 50722865-50779962

Description:

The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Pan troglodytes ,  Danio rerio ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  RTAAACA_FREAC2_01 ,  FREAC7_01 ,  OCT1_B ,  P53_DECAMER_Q2 ,  OCT1_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  HFH1_01 ,  OCT1_Q5_01 ,  OCT_C ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  P53_02 ,  GGGCGGR_SP1_Q6 ,  CCCNNGGGAR_OLF1_01 ,  MGGAAGTG_GABP_B ,  FOXO1_01 ,  HFH8_01 ,  AHRARNT_01 ,  TTGTTT_FOXO4_01 ,  SNACANNNYSYAGA_UNKNOWN ,  T3R_Q6 ,  GRE_C ,  ZF5_B

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Cytogenetic Map:

19q13.32

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