QuickView for Osteopontin (gene)
- Gene Symbol:
- Spp1
Rattus norvegicus - Full name:
- secreted phosphoprotein 1
- Synonyms:
- OSP, osteopontin, SPP-1, Sialoprotein (osteopontin), bone sialoprotein 1, osteopontin-like
- Genomic Location:
- Chr 14: 6422744-6426400
- Description:
-
sialoprotein that binds osteosarcoma cells; may play a role in osteoclast cell function
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
signaling receptor binding | molecular function regulator | extracellular matrix binding | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity
GO Biological Process
response to extracellular stimulus | positive regulation of macromolecule biosynthetic process | response to nutrient levels | response to cytokine | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cell development | regulation of localization | response to hormone | negative regulation of collateral sprouting of intact axon in response to injury | negative regulation of cellular process | cell differentiation | defense response | nervous system development | neurogenesis | positive regulation of cell adhesion | generation of neurons | regulation of lipid transport | regulation of bone remodeling | positive regulation of cellular biosynthetic process | cellular process | negative regulation of axonogenesis | organic substance catabolic process | localization | negative regulation of axon regeneration | negative regulation of developmental growth | regulation of estradiol secretion | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | granulocyte chemotaxis | tissue development | regulation of cell differentiation | regulation of cellular process | cellular response to lipid | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | response to stimulus | negative regulation of collateral sprouting | neutrophil chemotaxis | response to stress | negative regulation of neuron projection development | androgen metabolic process | regulation of neuron projection regeneration | positive regulation of hormone secretion | cellular response to organic cyclic compound | response to vitamin D | regulation of cellular component size | positive regulation of RNA biosynthetic process | regulation of cell adhesion | cell chemotaxis | molecular function regulator | leukocyte migration | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | locomotion | cellular response to hormone stimulus | system development | regulation of signal transduction | negative regulation of growth | multicellular organism development | cell migration | regulation of axonogenesis | steroid catabolic process | lipid metabolic process | regulation of hormone levels | regulation of hormone secretion | regulation of neuron differentiation | regulation of gene expression | positive regulation of secretion | response to ketone | cellular response to stress | response to lipid | cellular response to testosterone stimulus | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | cellular response to fluid shear stress | response to nutrient | cellular response to cytokine stimulus | positive regulation of lipid localization | negative regulation of response to wounding | androgen catabolic process | regulation of cellular metabolic process | response to testosterone | inflammatory response | leukocyte chemotaxis | regulation of RNA metabolic process | positive regulation of transport | negative regulation of cell growth | regulation of signaling receptor activity | receptor regulator activity | positive regulation of estradiol secretion | regulation of cell morphogenesis involved in differentiation | regulation of growth | response to organic substance | negative regulation of cell projection organization | hormone catabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | regulation of collateral sprouting of intact axon in response to injury | regulation of bone resorption | regulation of tissue remodeling | regulation of secretion | cell adhesion | receptor ligand activity | lipid catabolic process | cytokine activity | organic substance metabolic process | response to vitamin | animal organ development | negative regulation of neuron differentiation | positive regulation of cell-substrate adhesion | biomineral tissue development | regulation of axon regeneration | steroid metabolic process | regulation of collateral sprouting | response to fluid shear stress | regulation of response to wounding | regulation of cell communication | cellular response to leukemia inhibitory factor | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of developmental growth | regulation of cell size | hormone metabolic process | positive regulation of tissue remodeling | regulation of nervous system development | regulation of developmental process | negative regulation of neuron projection regeneration | developmental process | regulation of cell growth | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of bone resorption | positive regulation of nucleic acid-templated transcription | positive regulation of metabolic process | ossification | osteoblast differentiation | regulation of cell projection organization | positive regulation of lipid transport | immune system process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | negative regulation of cell development | neutrophil migration | chemotaxis | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | apical part of cell | Golgi apparatus | cell projection | endomembrane system | vesicle | perinuclear region of cytoplasm | extracellular region | membrane-bounded organelle | organelle | extracellular space | intracellular
