QuickView for PAK6;jsessionid=570F744727FC5536B7410B3E8E411FF0 (gene)
- Gene Symbol:
- PAK6
Homo sapiens - Full name:
- p21 (RAC1) activated kinase 6
- Synonyms:
- PAK5, serine/threonine-protein kinase PAK 6, p21 protein (Cdc42/Rac)-activated kinase 6, p21(CDKN1A)-activated kinase 6
- Genomic Location:
- Chr 15: 38319368-38356979
- Description:
-
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MA...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
TTTGCAC_MIR19A_MIR19B , TGANTCA_AP1_C , TTANTCA_UNKNOWN , RSRFC4_01 , EFC_Q6 , ATF4_Q2 , RSRFC4_Q2 , FXR_IR1_Q6 , AMEF2_Q6 , AP1_Q6
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-128 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-185 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-27 , Predicted Gene Targets for miR-323 , Predicted Gene Targets for miR-328 , Predicted Gene Targets for miR-339 , Predicted Gene Targets for miR-9
- Cytogenetic Map:
-
15q15.1
GO Molecular Function
GTPase binding | Rho GTPase binding | cadherin binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | Ras GTPase binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | cell adhesion molecule binding | purine ribonucleoside triphosphate binding | protein binding | Rac GTPase binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | small GTPase binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
intracellular signal transduction | positive regulation of phosphate metabolic process | cellular process | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | response to stimulus | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | protein serine/threonine kinase activity | programmed cell death | protein modification process | macromolecule modification | activation of protein kinase activity | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of phosphorylation | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | regulation of kinase activity | regulation of intracellular signal transduction | metabolic process | regulation of RNA biosynthetic process | protein kinase activity | organic substance metabolic process | cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | cytoskeleton organization | regulation of cell communication | signaling | regulation of transcription, DNA-templated | positive regulation of phosphorylation | cellular protein metabolic process | kinase activity | organelle organization | cellular protein modification process | positive regulation of metabolic process | cellular metabolic process | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | fibrillar center | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | cell junction
