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QuickView for PANX1 (gene)


Gene Symbol:
PANX1 Homo sapiens Homo sapiens
Full name:
pannexin 1
Synonyms:
MRS1, PX1, UNQ2529, pannexin-1, innexin
Genomic Location:
Chr 11: 93501742-93554786
Description:
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination w...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Bos taurus Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q21





GO Molecular Function

actin binding | actin filament binding | passive transmembrane transporter activity | enzyme binding | gap junction hemi-channel activity | protein-containing complex binding | transmembrane transporter activity | signaling receptor binding | gap junction channel activity | ion channel binding | cytoskeletal protein binding | leak channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | protein heterodimerization activity | scaffold protein binding | protein binding | wide pore channel activity | metal ion transmembrane transporter activity | protein dimerization activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | protease binding | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

response to extracellular stimulus | regulation of interleukin-1 beta production | protein hexamerization | response to nutrient levels | response to ATP | regulation of localization | establishment of localization | response to drug | positive regulation of interleukin-1 beta secretion | positive regulation of protein secretion | response to organophosphorus | cellular process | localization | passive transmembrane transporter activity | metal ion transport | gap junction hemi-channel activity | regulation of cellular process | transmembrane transporter activity | cellular component organization | regulation of peptide secretion | response to stimulus | positive regulation of interleukin-1 beta production | response to stress | gap junction channel activity | divalent metal ion transport | positive regulation of cytokine secretion | response to ischemia | regulation of protein transport | cellular component assembly | regulation of peptide transport | cell-cell signaling | positive regulation of peptide secretion | response to nitrogen compound | calcium ion transmembrane transport | response to purine-containing compound | protein complex oligomerization | ion transmembrane transport | leak channel activity | positive regulation of interleukin-1 alpha production | positive regulation of secretion | cation transmembrane transporter activity | response to nutrient | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | positive regulation of interleukin-1 secretion | regulation of interleukin-1 production | cell communication | positive regulation of interleukin-1 production | positive regulation of establishment of protein localization | positive regulation of transport | regulation of cytokine secretion | cation transmembrane transport | protein-containing complex assembly | regulation of establishment of protein localization | positive regulation of interleukin-1 alpha secretion | response to organic substance | wide pore channel activity | metal ion transmembrane transporter activity | regulation of interleukin-1 beta secretion | calcium ion transport | regulation of secretion | regulation of protein secretion | inorganic cation transmembrane transport | positive regulation of cytokine production | positive regulation of protein transport | cation channel activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | response to organic cyclic compound | regulation of cytokine production | cation transport | channel activity | calcium channel activity | regulation of transport | response to organonitrogen compound | ion channel activity | ion transport | regulation of protein localization | substrate-specific channel activity

GO Cellular Component

bleb | integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | cell-cell junction | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | endomembrane system | endoplasmic reticulum membrane | plasma membrane | gap junction | membrane-bounded organelle | organelle | cell periphery | intracellular | cell junction | membrane