QuickView for PAPPA2 (gene)

Gene Symbol:

PAPPA2 Homo sapiens

Full name:

pappalysin 2

Synonyms:

PAPP-A2, PAPP-E, PAPPE, PLAC3, pappalysin-2, placenta-specific 3, pregnancy-associated plasma preproprotein-A2, pregnancy-associated plasma protein E1

Genomic Location:

Chr 1: 174698930-175078595

Description:

This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

1q25.2

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