QuickView for PARG (gene)

Gene Symbol:

PARG Homo sapiens

Full name:

poly(ADP-ribose) glycohydrolase

Synonyms:

PARG99, poly(ADP-ribose) glycohydrolase, mitochondrial poly(ADP-ribose) glycohydrolase, poly(ADP-ribose) glycohydrolase 60 kDa isoform

Genomic Location:

Chr 10: 51293430-51377668

Description:

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for...

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Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATTCTTT_MIR186 ,  ACCAAAG_MIR9 ,  TGGTGCT_MIR29A_MIR29B_MIR29C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-29

Cytogenetic Map:

10q11.23

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